In a saucepan on medium heat, put Tomato Ketchup, Brown Sugar, Yellow Mustard, Apple Cider Vinegar, Worcestershire Sauce, Chili Powder, Smoked Paprika, Garlic Powder, Salt, and Ground Black Pepper.
Stir everything together until it's mixed well, and let it start to simmer.
Turn down the heat to low and allow the sauce to simmer for around 15 minutes, until it gets thicker.
Now, you can enjoy your homemade BBQ sauce on your favorite BBQ meats or vegetables.